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The Dreaded TB Skin Test
Tshering D. Amdo, M.D.

I think that a lot of people from the Himalayan region are having increased access to proper health care nowadays. More people are undergoing routine screening physical examination as part of the immigration process. One common denominator seems to be the TB skin test. You get the TB skin test on your forearm and — lo and behold — after two to three days you have a nice little plum growing on your forearm that hurts, gets red and itches. You go to the doctor's office and the nurse reading the test gives you a suspicious look and runs to get the doctor. She might come back wearing a gas mask or might just talk to you from across the room. Does it mean that you have tuberculosis? YES & NO!

Historically Tibetans and all people who live in the Himalayan belt are predisposed to acquiring TB due to various factors. Moreover India, Nepal and Tibet are countries where Tuberculosis (TB) is prevalent and endemic. Children in India and Nepal are also routinely vaccinated with BCG vaccine to prevent TB. So almost everybody coming from these countries has been exposed to TB at some point in their life — unless you lived your entire life in a bubble! It's a very common thing to have someone in your family who has had TB and its subsequent treatment.

Don't worry — they inject only proteins derived from TB. They are not injecting any live bugs in you."

The skin test is done to check whether you have TB, been exposed to it, or to rule out TB. It's an injection on your forearm, which gets marked, and you have to come back in 2-3 days to get it read. They check to see how much of a reaction you have to the stuff they inject under your skin. Don't worry — they inject only proteins derived from TB. They are not injecting any live bugs in you.

One has to measure the size of the induration (lump), not the size of the redness. If you don't have a reaction, you can rest in peace and stop reading the rest of this article.

For people coming from endemic areas i.e. India, Nepal, Tibet, China, if the lump on the forearm is more than 10mm, it is considered a positive test. BUT that still does not mean that you have TB — don't start sweating yet. The doctor will ask you questions as to whether you have had TB in the past, exposure to people with TB, coughing, coughing up blood, fevers, night sweats, weight loss, loss of appetite.

The next step is a chest x-ray. If the chest x-ray shows signs consistent with TB then one undergoes treatment for it. If the chest x-ray is normal, it is considered that you have been exposed to TB in the past and would be termed as having latent tuberculosis that could potentially turn into active TB later. This is treated with a single drug (INH — Isoniazid) for nine months on a daily basis. The drug itself can cause side effects like liver dysfunction. Therefore I would advise people to avoid drinking alcohol while on this medication.

I have tried to make it as simple as possible by minimizing use of medical jargon. There are exceptions and variations to how the test is read. Getting into those details would make it confusing.

If you have any further questions, please direct it migyul@yahoo.com and the editors can forward it to me.